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Scott Parker Selected Research

Infectious Ectromelia

11/2021A human recombinant analogue to plasma-derived vaccinia immunoglobulin prophylactically and therapeutically protects against lethal orthopoxvirus challenge.
3/2017Buccal viral DNA as a trigger for brincidofovir therapy in the mousepox model of smallpox.
11/2014Co-administration of the broad-spectrum antiviral, brincidofovir (CMX001), with smallpox vaccine does not compromise vaccine protection in mice challenged with ectromelia virus.
4/2012Evaluation of disease and viral biomarkers as triggers for therapeutic intervention in respiratory mousepox - an animal model of smallpox.
3/2009Mousepox in the C57BL/6 strain provides an improved model for evaluating anti-poxvirus therapies.
1/2008Using biomarkers to stage disease progression in a lethal mousepox model treated with CMX001.
1/2008Efficacy of therapeutic intervention with an oral ether-lipid analogue of cidofovir (CMX001) in a lethal mousepox model.
4/2007Induction of natural killer cell responses by ectromelia virus controls infection.

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Scott Parker Research Topics

Disease

10Infections
03/2020 - 04/2007
10Smallpox (Variola)
10/2017 - 01/2008
8Infectious Ectromelia
11/2021 - 04/2007
5Mpox (monkeypox)
03/2017 - 01/2008
5Ectromelia (Phocomelia)
09/2015 - 03/2009
4Neoplasms (Cancer)
01/2019 - 05/2010
3Poxviridae Infections
01/2012 - 02/2007
2Vaccinia
11/2021 - 07/2009
2Pain (Aches)
01/2019 - 06/2014
2Weight Loss (Weight Reduction)
01/2008 - 01/2008
1Severe Dengue
03/2020
1Brain Neoplasms (Brain Tumor)
01/2019
1Glioblastoma (Glioblastoma Multiforme)
01/2019
1Glioma (Gliomas)
01/2019
1Pruritus (Itching)
06/2014
1Anthrax
06/2014
1Polycythemia (Erythrocytosis)
08/2013
1Retinal Degeneration
08/2013
1Exanthema (Rash)
04/2012
1Heart Diseases (Heart Disease)
07/2009
1Cytomegalovirus Retinitis
01/2008
1Disease Progression
01/2008
1Acquired Immunodeficiency Syndrome (AIDS)
01/2008
1Muscular Diseases (Myopathy)
09/2007
1Muscular Dystrophies (Muscular Dystrophy)
09/2007
1Body Weight (Weight, Body)
02/2007

Drug/Important Bio-Agent (IBA)

11Antiviral Agents (Antivirals)IBA
11/2021 - 04/2007
8brincidofovirIBA
10/2017 - 01/2008
6VaccinesIBA
11/2021 - 11/2008
4tecovirimatIBA
10/2017 - 02/2007
3Proteins (Proteins, Gene)FDA Link
01/2019 - 08/2014
3Viral DNAIBA
03/2017 - 01/2008
3Cidofovir (Vistide)FDA Link
04/2010 - 01/2008
2AntigensIBA
01/2019 - 03/2009
2Biological Warfare AgentsIBA
10/2017 - 04/2012
2ACAM2000IBA
11/2014 - 07/2009
2Biomarkers (Surrogate Marker)IBA
04/2012 - 01/2008
2Indicators and Reagents (Reagents)IBA
04/2012 - 04/2010
1Immunoglobulins (Immunoglobulin)IBA
11/2021
1Interleukin-4 (Interleukin 4)IBA
11/2021
1AZD 6244IBA
03/2020
1Immune Checkpoint InhibitorsIBA
01/2019
1epidermal growth factor receptor VIIIIBA
01/2019
1Immunotoxins (Immunotoxin)IBA
01/2019
1ErbB Receptors (EGF Receptor)IBA
01/2019
1Tyrosine Kinase InhibitorsIBA
12/2018
1Spectinomycin (Spectinomycin Hydrochloride)FDA Link
01/2017
1Formaldehyde (Formol)FDA Link
06/2016
1Complement System Proteins (Complement)IBA
06/2016
1ParaffinIBA
06/2016
1EpitopesIBA
09/2015
1Anthrax Vaccines (Vaccines, Anthrax)IBA
06/2014
1Immunoglobulin G (IgG)IBA
06/2014
1ProgesteroneFDA LinkGeneric
06/2014
1Trans-Activators (Trans-Acting Factor)IBA
08/2013
1ErythropoietinFDA Link
08/2013
1Tetracycline (Achromycin)FDA LinkGeneric
08/2013
1Pharmaceutical PreparationsIBA
09/2010
1Temozolomide (Temodar)FDA LinkGeneric
05/2010
1Carmustine (FIVB)FDA Link
05/2010
1Smallpox Vaccine (Vaccine, Smallpox)FDA Link
07/2009
1Viral VaccinesIBA
07/2009
1CytokinesIBA
03/2009
1Therapeutic UsesIBA
11/2008
1LipidsIBA
01/2008
1Alanine Transaminase (SGPT)IBA
01/2008
1Biological ProductsIBA
01/2008
1Interferon-gamma (Interferon, gamma)IBA
01/2008
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2008
1Ether (Diethyl Ether)IBA
01/2008
1EstersIBA
01/2008
1Caveolin 3IBA
09/2007
1Caveolin 1IBA
09/2007
1LigandsIBA
04/2007

Therapy/Procedure

8Therapeutics
01/2019 - 01/2008
1Analgesia
01/2019
1Injections
06/2014
1Contraindications
07/2009
1Treatment Delay
02/2007